ODCs

Click node...

1 OMIM reference -
2 associated genes
4 signs/symptoms

PROTEIN INTERACTIONS: 2
COMMON SIGNS: 1

3 OMIM references -
3 associated genes
4 signs/symptoms

Localized epidermolysis bullosa simplex

Keratosis palmoplantaris striata


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	KRT5 KRT5	(0.58) (0.52)	DSP KRT1

Citations in the biomedical literature:

Localized epidermolysis bullosa simplex		Keratosis palmoplantaris striata
	Synonym(s): - EBS-loc - Epidermolysis bullosa simplex of palms and soles - Epidermolysis bullosa simplex, Weber-Cockayne type		Synonym(s): - Keratosis palmoplantaris striata et areata - Keratosis palmoplantaris varians of Wachters - Striate palmoplantar keratoderma

	Classification (Orphanet): - Rare genetic disease - Rare skin disease		Classification (Orphanet): - Rare genetic disease - Rare skin disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: 1-9 / 1 000 000 Average age onset: childhood Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: - Average age onset: - Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 3 OMIM references - No MeSH references


COMMON SIGNS	- Autosomal dominant inheritance

Localized epidermolysis bullosa simplex		Keratosis palmoplantaris striata
	Very frequent - Ecchymoses - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment Frequent - Hyperhidrosis / increased sweating		Very frequent - Palmoplantar hyperkeratosis / keratoderma Frequent - Hair and scalp anomalies - Nails anomalies